Animals die during hibernation (difficulty in conditioning).
Natural reproduction is unsuccessful (hormonal induction).
Poor survival or growth to maturity (squamous metaplasia & odema).
A costly program is implemented  involving two federal hatcheries and 12 zoos to produce about 8000 tadpoles a year (same as three clutches).
Research needed to improve fecundity (hormones) and survival (better husbandry).
Problems Associated with Captive Breeding of Wyoming Toads.